1 mCi = 1000 uCi
We typically administer 160 uCi/g thyroid tissue [5.9 MBq/g] for Graves' hyperthyroidism and 200 uCi/g [7.4 MBq/g] for toxic adenoma/MNG. A fixed dose of 10 to 15 mCi [370 to 555 MBq] for Graves and 15 to 20 mCi [500 to 740 MBq] for toxic adenoma/MNG is an alternative option.
For patients with significant symptoms of hyperthyroidism and in elderly patients with underlying cardiac disease, we suggest starting a methimazole to achieve euthyroidism prior to radioiodine therapy.
We discontinue methimazole three days prior to radioiodine and restart three days after radioiodine therapy.
For young and middle-aged patients who are less symptomatic, there is no need to pretreat with a thionamide, and radioiodine can be given soon after the diagnosis is made.
