In patients with mild to moderate hypertriglyceridemia (150 to 500 mg/dL), the main indication for therapy is reduction of cardiovascular (CV) risk. Lifestyle changes are a central part of managing such patients. Pharmacologic therapy with statin therapy for CV risk reduction has been best proven. Benefit from lowering the cholesterol with statins in patients without clinical evidence of CVD has also been demonstrated. Besides, glucocorticoids may cause peripheral insulin resistance, hyperinsulinemia, and increased VLDL synthesis.
沒有留言:
張貼留言