Subclinical hypothyroidism

For patients with subclinical hypothyroidism and TSH concentrations ≥10 mU/L, we suggest treatment with thyroid hormone (T4).

For non-older patients with TSH concentrations between 4.5 and 10 mU/L who have symptoms of hypothyroidism, we also suggest treatment with T4.

For older patients (over age 70 years) with subclinical hypothyroidism and TSH between 4.5 and 8 mU/L, we suggest "not" treating.

We recommend initiating T4 replacement in women with subclinical hypothyroidism (TSH values >2.5 mU/L) who are pregnant.