~A Boy Always Young~

2015年9月8日 星期二

Test for Cushing



## Low dose dexamethasone suppression test:
1. Dexamethasone 0.5mg 1# q6h since 9/11~9/12 (at 8AM, 2PM, 8PM, 2AM), total 2days=8 dose  
2. Collect 24 hours(9/12 08:00 ~ 9/14 08:00) Urine 17-OHC, cortisol x 2 days
3. check serum ACTH, cortisol on 9/13 8AM
異常:urine cortisol > 36mcg/day, serum cortisol > 1.4mcg/dL

## High dose dexamethasone suppression test:
1. Dexamethasone 0.5mg 4# q6h since 9/14~9/15(at 8AM, 2PM, 8PM, 2AM), total 8 dose (16mg)
2. Collect 24 hours(9/16 08:00 ~9/17 08:00) Urine 17-OHC, cortisol x 2 days
3. check serum ACTH, cortisol on 9/16 8AM
如果能夠把baseline的urine cortisol抑制90%以上-->猜cushing disease
read more